Melatonin-d3 is the deuterium labeled version of Melatonin. Melatonin is a hormone that activates melatonin receptors, playing a role in sleep and possessing antioxidative and anti-inflammatory properties. It is also identified as a selective ATF-6 inhibitor, inducing apoptosis in human hepatoma cells by downregulating COX-2, and can reduce palmitic acid-induced apoptosis in mouse granulosa cells by alleviating endoplasmic reticulum stress.
- Used as a tracer
- Serves as an internal standard for quantitative analysis
- Stable heavy isotopes for drug development quantitation
- Deuteration can influence pharmacokinetic and metabolic profiles
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Solvent storage: -80°C for 6 months, -20°C for 1 month